Description
Therapeutic action
– Antiemetic (dopamine antagonist)
Indications
– Symptomatic treatment of nausea and vomiting in adults
Presentation
– 10 mg tablet
Dosage
– Adult under 60 kg: 15 mg/day in 3 divided doses
– Adult over 60 kg: 30 mg/day in 3 divided doses
The interval between each dose should be at least 6 hours (even in the event of vomiting).
Duration
– A few days
Contra-indications, adverse effects, precautions
– Do not administer to children < 18 years and to patients with gastrointestinal haemorrhage, obstruction
or perforation.
– Reduce the dose by half in patients with severe renal impairment.
– Administer with caution and monitor use in patients > 60 years and patients with epilepsy or Parkinson’s
disease.
– May cause: drowsiness (caution when driving/operating machinery), dizziness, confusion, extrapyramidal
symptoms, seizures (especially in epileptics), allergic reactions; neuroleptic malignant syndrome
(unexplained hyperthermia with neuromuscular disorders), exceptional but requiring immediate
treatment discontinuation.
– Do not combine with levodopa (antagonism).
– Avoid combination with CNS depressants (opioid analgesics, antipsychotics, sedatives, antidepressants,
antihistamines, etc.).
– Avoid alcohol during treatment.
–Pregnancy: no contraindication
–Breast-feeding: no contraindication
Remarks
– Storage: below 25°C – –
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