Description
Therapeutic action
– Diuretic
Indications
– Moderate or severe hypertension
– Oedema caused by renal, hepatic or congestive heart failure
Presentation
– 50 mg tablet
Also comes in 25 mg tablet.
Dosage
– Hypertension
Adult: 25 to 50 mg/day in 2 divided doses
–Oedema
Child: 1 mg/kg/day in 2 divided doses
Adult: 50 to 100 mg in the morning, on alternate days
Duration
– According to clinical response
Contra-indications, adverse effects, precautions
– Do not administer if severe renal failure, allergy to sulphonamides; for other types of oedema, especially
those due to kwashiorkor.
– May cause: dehydration, hypotension, hypokalaemia, photosensitivity, hyperglycaemia.
–Pregnancy: contra-indicated
– Breast-feeding: contra-indicated
Remarks
– Often used in combination with an antihypertensive drug.
– A lot of fruit should be eaten during treatment (dates, bananas, mangos, oranges, etc.), in order to.





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