Description
Therapeutic action
– Diuretic
Indications
– Oedema caused by renal, hepatic or congestive heart failure
– Hypertension (prefer hydrochlorothiazide for this indication)
Presentation
– 20 mg and 40 mg tablets
Dosage
– Child: 1 to 2 mg/kg once daily
– Adult: 20 to 40 mg once daily
– Reduce doses according to clinical response.
– In case of persistant oedema: 80 to 150 mg once or in 2 divided doses, then reduce dosage.
Duration
– According to clinical response
Contra-indications, adverse effects, precautions
– Do not administer for other types of oedema, especially those due to kwashiorkor.
– May cause:
- hypokalaemia (especially in case of cirrhosis), poor nutritional status, congestive heart failure
(furosemide enhances toxicity of digoxin);
–dehydration and orthostatic hypotension.
Pregnancy
: avoid; do not use for hypertension in pregnancy.
–Breast-feeding: avoid (excreted in milk and may reduce milk production)
Remarks
– Give in the morning.
– A lot of fruit should be eaten during treatment (dates, bananas, mangos, oranges, etc.) in order to supply
additional potassium. Use potassium tablets as well if available
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