Ciproflaxin 500mg 100s

Description

Therapeutic action

– Fluoroquinolone antibacterial

Indications

– Shigellosis, typhoid fever, cutaneous anthrax

– Uncomplicated acute cystitis in non-pregnant women or in the event of previous treatment failure,

acute prostatitis, uncomplicated acute pyelonephritis, chancroid

Presentation

– 250 mg and 500 mg tablets

– 250 mg/5 ml granules and solvent for oral suspension

Dosage

– Shigellosis, typhoid fever, cutaneous anthrax

Child over 1 month: 30 mg/kg/day in 2 divided doses (max. 1 g/day)

Adult: 1 g/day in 2 divided doses

– Uncomplicated acute cystitis in non-pregnant women

Adult: 500 mg/day in 2 divided doses

–

Acute cystitis (in the event of recurrence or treatment failure), acute prostatitis, chancroid

Adult: 1 g/day in 2 divided doses

–

Uncomplicated acute pyelonephritis

Adult: 1 to 1.5 g/day in 2 to 3 divided doses

Duration

– Shigellosis, uncomplicated cystitis, chancroid

: 3 days; cystitis (in the event of recurrence or treatment failure)

5 days; typhoid fever: 5 to 7 days; pyelonephritis: 7 days;

Contra-indications, adverse effects, precautions

cutaneous anthrax: 7 to 10 days; prostatitis: 28 days

– Do not administer to patients with history of allergy or tendinitis due to fluoroquinolones.

– Administer with caution to epileptic patients (risk of seizures).

– Reduce the dose by half in patients with renal impairment.

– May cause: gastrointestinal disturbances, neurological disorders (headache, dizziness, confusion,

hallucinations, seizures), allergic reaction, peripheral neuropathy, photosensitivity (protect skin from sun

exposure), arthralgia, myalgia, tendon damage (especially Achilles tendinitis), QT interval prolongation,

hypo/hyperglycaemia, haemolytic anaemia in patients with G6PD deficiency. In the event of allergic

reaction, severe neurological disorders, peripheral neuropathy or tendinitis, stop treatment immediately.

– Avoid combination with drugs that prolong the QT interval (amiodarone, chloroquine, co-artemether,

fluconazole, haloperidol, mefloquine, ondansetron, pentamidine, quinine, etc.).

– Monitor patients taking glibenclamide (risk of hypoglycaemia).

– Do not administer simultaneously with antacids (aluminium or magnesium hydroxide, etc.), iron salts,

calcium. Administer 2 hours apart.

– Drink a lot of liquid during treatment (risk of crystalluria).

Pregnancy

: reserved for severe infections, when there is no therapeutic alternative.

Breast-feeding: no contra-indicatioN