Diclofenac IM 75mg/3ml

Description

THERAPEUTIC ACTION – Non-steroidal anti-inflammatory drug, analgesic, antipyretic INDICATION – Moderate pain, particularly due to inflammation (acute sciatic neuralgia, renal colic, postoperative pain etc.) Presentation and route of administration – 75 mg in 3 ml ampoule (25 mg/ml) for deep IM injection or infusion DOSAGE – Adult : 75 mg by deep IM injection; combine with 50 mg by oral route if necessary – For postoperative pain, may be administered by infusion: 75 mg over 30 to 120 minutes; to be repeated after 4 to 6 hours if necessary. Maximum dose: 150 mg/day DURATION – Maximum 2 to 3 days; change to oral treatment as soon as possible. Contra-indications, adverse effects, precautions DONTS – Do not administer in case of: • renal impairment, uncorrected dehydration or hypovolaemia, severe malnutrition; • peptic ulcer; • hypersensitivity to other NSAID (aspirin, ibuprofen, indometacin etc.), hepatic impairment, severe infection; • coagulation defects, surgery with risk of major blood loss. – May cause: renal impairment, gastrointestinal disturbances, allergic reactions (rash, eczema, bronchospasm). – Administer with caution to elderly or asthmatic patients. – Do not combine with other NSAID (aspirin, ibuprofen, indometacin etc.), diuretics, anticoagulants. – Pregnancy : contra -indicated – Breast-feeding : contra -indicated REMARKS – For infusion, use a solution of 5% glucose or 0.9% sodium chloride and add 0.5 ml of 8.4% sodium bicarbonate per 500 ml. – Diclofenac is not included in the WHO list of essential medicines.

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