Description
THERAPEUTIC ACTION
– Anthelminthic INDICATION
– Ascariasis ( Ascaris lumbricoides ), enterobiasis ( Enterobius vermicularis ), hookworm infections (Ancylostoma duodenale ,Necator americanus ) – Trichuriasis (Trichuris trichiura), strongyloidiasis ( Strongyloides stercoralis ) – Trichinellosis ( richinella spp)
PRESENTATION – 400 mg tablet, 1OML syrup
DOSAGE and duration
– Ascariasis, enterobiasis, hookworm infections Child over 6 months and adult: 400 mg as a single dose Child over 6 months but under 10 kg: 200 mg as a single dose In the event of enterobiasis, a second dose may be given after 2 to 4 weeks. – Trichuriasis, strongyloidiasis Child over 6 months and adult: 400 mg once daily for 3 days Child over 6 months but under 10 kg: 200 mg once daily for 3 days – Trichinellosis Child over 2 years: 10 mg/kg/day in 2 divided doses for 10 to 15 days Adult: 800 mg/day in 2 divided doses for 10 to 15 days
PRECAUTIONS
– Do not administer to children under 6 months. – Do not administer to patients with ocular cysticercosis. – May cause: • gastrointestinal disturbances, headache, dizziness; – • neurological disorders (headache, seizures) in patients with undiagnosed neuro cysticercosis. Pregnancy: avoid during the first trimester – Breast-feeding : no contra-indication
REMARKS
– Tablets are to be chewed or crushed: follow manufacturer’s recommendations. – In the treatment of strongyloidiasis, ivermectin is more effective than albendazole. – Albendazole is also used in the treatment of cutaneous larva migrans ( Ancylostoma braziliense and caninum ), larval cestode infections (hydatid disease, certain forms of neurocysticercosis) and in mass treatment for lymphatic filariasis
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